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June 2004 schedule of  rat & raclopride studies                    
                             
Day subjects prior arterial cannulation of rats required? time rats arrive at IndyPET scanning start time  Jan F's personnel? Gamma Counter needed? Ethanol? tracer (# syntheses) blood processing        
  rats humans                        
                             
                             
3-Jun 2 0 Yes 12:45pm 1:15, 2:30 Yes. Matthew to draw blood Yes. 1:30 - 5:00 No FDG Karmen        
4-Jun 2 0 Yes 12:45pm 1:15, 2:30 No. Karmen to draw blood Yes. 1:30 - 5:00 No FDG Marc        
                             
                             
7-Jun 2 0 No 12:45pm 1:15 (rat 1), 2:30 (rat 2) Yes (give EtOH) No Matthew to give EtOH 1.5 mg/kg ip to rat 2 at 12:30 (2 hours before injection) and rat 1 at 1:15 (@ time of inj) raclo(2) none        
8-Jun (2) rats from previous day to be rescanned on this day   2 No 9:15am ~10:30 (rat 1), ~2:00 (rat 2) No. Yes. 11:00-4:00 No raclo(2)  Extra 1 mCi from each synthesis for human Karmen to process HUMAN blood        
                             
                             
                             
15-Jun 2 2 No 9:15am ~10:30 (rat 1), ~2:00 (rat 2) No. Yes. 11:00-4:00 No raclo(2)  Extra 1 mCi from each synthesis for human Karmen to process HUMAN blood        
16-Jun (2) rats from previous day to be rescanned on this day   0 no 9:15am 10:00 (rat 1), 11:30 (rat 2) Yes (give EtOH) No Matthew to give EtOH 1.5 mg/kg ip to rat 2 at 9:30 (2 hours before injection) and to rat 1 at 10:00 (@ time of injection) raclo(2) none        
                             
                             
                             
9-Aug 3 2 no 10:00am 11:00am (rat A, high SA)  1:45pm (rat B, high SA) 2:45pm (rat C, low SA) no no no raclo (2) extra 1mCi from first synth for human, extra 5+mCi from second none        
9-Aug (updated) 1 1 no 10:00am 11:00am (rat27, high SA) no no no raclo, one successful synthesis none        
10-Aug 2 (rescanned from 8/9) 1 no 12:45pm 1:45 pm (rat A, high SA) 2:45pm (rat B, low SA) no no no raclo (1) extra 5+mCi from synthesis for human none        
10-Aug (updated) 2 (rat26 rescanned from 8/9) 1 no 1:30pm 2:15pm (rat26, high SA) 3:15pm (rat27, low SA) no no no raclo (1) extra 5+mCi from synthesis for human none        
13-Aug (new addition) 2 (rat 26 rescanned from 8/9, rat27 rescanned from 8/10) 0 no TBA TBA (rat26, high SA)   TBA (rat27, low SA) no no no raclo (1)  none        
                             
                             
                             
19-Aug 2 2 yes 10:00am 11:00am (rat D)      1:45pm (rat E)               No scanning -- blood sampling w/o imaging No, Karmen and Marc draw blood. yes             11:30-4:00 no raclo (2) extra 1mCi from each of the syntheses for human Marc/Karmen        
20-Aug 1 1 yes 12:45pm 1:45 pm (rat F)              No scanning -- blood sampling w/o imaging No, Karmen draws blood. yes              2:00-4:00 no raclo (1) extra 1mCi from synthesis for human ?