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CLA: |
Imaging Drugs in the Brain
with PET |
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Instructor: |
Morris
(emorris@iupui.edu)
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Time: |
Fridays, 3:30-5:20pm |
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Place: |
SL220
conference room - or by video hookup |
(IUPUI
campus)
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IT Contact
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MJIS 1083
Jim Jones (WLareacode)337-8861
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(Purdue Campus)
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paper
summary prep hints
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| Date |
Class |
Paper 1 |
Paper 2 |
Presenter 1 |
Presenter 2 |
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"Application
Paper"
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"Modeling
Paper"
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31-Oct
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1
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Imaging
Dopamine Receptors in the Human Brain by Positron Tomography.
Wagner et al 1983, Science |
A
Quantitative Model for the In Vivo Assessment of Drug Binding Sites
with Positron Emission Tomography. Mintun et al 1984, Ann Neurol |
E Morris
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E Morris
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sample
summary
document
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sample summary
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one paper with modeling
and experimental design
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7-Nov
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2
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Comparison
of bolus and infusion methods for receptor quantitation:
application to [18F]cyclofoxy and positron emission tomography.
Carson et al. 1993 JCBF&M
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Y Weng
M Floyd
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notes on
volume of
distribution |
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two papers looking at
effects of endogenous dopamine from two different standpoints
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14-Nov
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3
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Effects
of endogenous dopamine on measures of [18F]N-methylspiroperidol
binding in the basal ganglia: Comparison of simulations and
experimental results from PET studies in baboons.
Logan et al 1993, Synapse
Effects
of endogenous dopamine on kinetics of [3H]N-methylspiperone
and [3H]raclopride binding in the rat
brain , Young et al. Synapse, 1993
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Presenter 1:
(supporting info)
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??
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In vivo imaging of
neuromodulation using PET: Optimal ligand characteristics and task
length for detection of activation. Morris et al, Human Brain
Mapping, 1995
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Presenter
2: ??
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21-Nov
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4
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Feeding-induced
dopamine release in dorsal striatum correlates with meal pleasantness
ratings in healthy human volunteers. Dana M. Small, Marilyn
Jones-Gotman and Alain Dagher. Neuroimage 2003
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| Evidence
for Striatal Dopamine Release
During
a Video Game" Koepp
et al, Nature vol 393, 1998, |
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5-Dec
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5
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